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They are regulated by the intracellular level of ATP as well as by various nucleotide diphosphates, pH and lactate concentrations. I’ve only known about 15 people who have experienced this out of all the people I have come in contact with who have used DNP in the past. While mild diuretics like alcohol will make you much more uncomfortable and hotter, a harsh diuretic like lasix will kill you when taken with DNP.
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